Simplify Your Buffer Preparation with Westlab's Comprehensive Calculator

Tired of tedious buffer calculations or inconsistent pH results? Westlab's Comprehensive Buffer Preparation Calculator is designed to save you time and ensure accuracy in the lab.

This versatile tool helps you determine the precise amounts of components needed to create a buffer solution with your desired pH, Molarity, and Volume. It supports multiple common preparation methods:

    • Mixing the weak acid and conjugate base salt forms.

    • Titrating the weak acid form with a strong base (e.g., NaOH).

    • Titrating the weak base form with a strong acid (e.g., HCl).

    • Mixing stock solutions of the acid and base forms.

Featuring built-in pKa and formula weight data for common buffers (like Tris, Phosphate (Na/K), HEPES, Acetate, etc.) and the flexibility to input custom buffer details (including handling for hydrated salts), this calculator streamlines the process. It even allows you to factor in an additional common salt (like NaCl) if needed.
Get a clear, step-by-step recipe including component masses/volumes, calculated concentrations, the effective buffering range, and preparation instructions. Reduce calculation errors, ensure reproducibility, and spend less time calculating and more time experimenting!

Comprehensive Buffer Preparation Calculator

Comprehensive Buffer Preparation Calculator

Calculate component amounts for buffer solutions based on target pH, molarity, and volume. Choose your preparation method and specify if using hydrated salts for custom buffers.

Target Buffer Parameters

Buffer System & Preparation Method

Select buffer to auto-fill pKa/FWs (anhydrous assumed), or choose Custom.
i CUSTOM BUFFERS ONLY: If using a hydrated salt, check box & enter number of waters (x) per formula unit (e.g., 7 for Na₂HPO₄·7H₂O). Mass calculated will be for the hydrated form.
i CUSTOM BUFFERS ONLY: If using a hydrated salt, check box & enter number of waters (x) per formula unit.

Additional Components

Calculate the amount needed for one extra non-buffering component (e.g., NaCl).


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